Endocrine Abstracts

Papillary carcinoma (PC) represents the most common malignancy of the thyroid gland. Therefore, the assessment of biopsies of thyroid nodules rests heavily on the identification of malignant from benign features. Unfortunately, up to 60% of biopsies are considered inadequate due to sampling artifact, insufficient material, or marked inter-observer variation. Proposed molecular markers of PC include HBME-1, specific cytokeratins such as CK19, and the tyrosine kinase receptor (r...